Titus, AJ, Way, GP, Johnson, KC, Christensen, BC. Deconvolution of DNA methylation identifies differentially methylated gene regions on 1p36 across breast cancer subtypes. Scientific Reports, 7:11594, 2017.
Salas, LA, Johnson, KC, Koestler, DC, O’Sullivan, DE, Christensen, BC. Integrative epigenetic and genetic pan-cancer somatic alteration portraits. Epigenetics 12(7):561-574, 2017.
Wiencke, JK, Koestler, DC, Salas, LA, Wiemels, JL, Roy, RP, Hansen, HM, Rice, T, McCoy, LS, Bracci, PM, Molinaro, AM, Kelsey, KT, Wrensch, MR, Christensen, BC. Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival. Clinical Epigenetics, 9(10), 2017.
Wilkins, OM, Titus, AJ, Gui, J, Eliot, M, Butler, RA, Sturgis, EM, Li, G, Kelsey, KT, Christensen, BC. Genome-scale identification of microRNA-related SNPs associated with risk of head and neck squamous cell carcinoma. Carcinogenesis, 38(10):986-993, 2017.
Johnson, KC, Houseman, EA, King, JE, von Hermann, KM, Fadul, CE, Christensen, BC. 5-hydroxymethylcytosine localizes to enhancer elements and is associated with patient survival in glioblastoma. Nature Communications, 7, 13177 doi:10.1038/ncomms13177, 2016.
Houseman, EA, Johnson, KC, Christensen, BC. OxyBS: Estimation of 5-methylcytosine and 5-hydroxymethylcytosine from tandem treated oxidative bisulfite and bisulfite DNA. Bioinformatics,32(16):2505-2507, 2016
Titus, AJ, Houseman, AE, Johnson, KC, Christensen, BC. methyLiftover: cross-platform genomic DNA methylation data integration. Bioinformatics, 32(16):2517-2519, 2016
Koestler, DC, USset, J, Christensen, BC, Marsit, CJ, Karagas, MR, Kelsey, KT, Wiencke, JK. DNA methylation-derived neutrophil-to-lymphocyte ratio (mdNLR): an epigenetic tool to explore cancer inflammation and outcomes. Cancer Epidemiology Biomarkers and Prevention, 26(3):328-338, 2016
Koestler, DC, Jones, MJ, Usset, J, Christensen, BC, Butler, RA, Kober, MS, Wiencke, JK, Kelsey, KT. Improving cell mixture convolution by identifying optimal DNA methylation libraries (IDOL). BMC Bioinformatics, 2016.
O'Sullivan, DE, Johnson, KC, Skinner, L, Koestler, DC, Christensen, BC. Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma. Epigenetics, 2016.
Green, BB, Houseman, EA, Johnson, KC, Guerin, DJ, Armstrong, DA, Christensen, BC, Marsit, CJ. 5-hydroxymethylcytosine and 5-methylcytosine are uniquely distributed within the term placenta epigenome and are associated with gene expression. (In Press), The FASEB Journal, 2016.
Johnson KC, Koestler DC, Fleischer T, Chen P, Jensen EG, Marotti EG, Onega T, Kristensen VN, Christensen BC. DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer. Clinical Epigenetics 2015.
Johnson KC, Koestler DC, Cheng C, Christensen BC. Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation. Epigenetics 2014
Fleischer, T, Johnson, KC, Edvardsen, H, Touleimat, N, Klajic, J, Riis, MLH, Haakensen, VD, Wärnberg, F, Naume, B, Helland, A, Børresen, AL, Tost, J, Frigessi, A, Christensen, BC, Kristensen, VN. Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis. Genome Biology 2014
Ung, M, Ma, X, Johnson, KC, Christensen, BC, Cheng, C. Effect of estrogen receptor alpha binding on functional DNA methylation in breast cancer. Epigenetics 2014.
Langevin, SM, Christensen, BC. Let-7 microRNA binding-site polymorphism in the 3’ UTR of KRAS and colorectal cancer outcome: a systematic review and meta-analysis. Cancer Medicine 2014.
Houseman, EA, Accomando, WP, Koestler, DC, Christensen, BC, Marsit, CJ, Nelson, HH, Wiencke, JK, Kelsey, KT. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 2012
Christensen, BC, Smith, AS, Zheng, S, Koestler, DC, Houseman, EA, Marsit, CJ, Wrensch, MR, Wiemels, JL, Nelson, HH, Karagas, MR, Kelsey, KT, Wiencke, JK. DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. Journal of the National Cancer Institute 2011
Christensen, BC, Avissar-Whiting, M, Oullet, LG, McClean, MD, Marsit, CJ, Kelsey, KT. Mature miRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer. Clinical Cancer Research 2011.
Christensen, BC, Houseman, EA, Poage, GM, Godleski, JJ, Bueno, R, Sugarbaker, DJ, Wiencke, JK, Nelson, HH, Marsit, CJ, Kelsey, KT. Integrated profiling of DNA methylation and copy number reveals global, not local correlation between epigenetic and genetic alterations in pleural mesothelioma. Cancer Research 2010
Christensen, BC, Houseman, EA, Marsit, CJ, Zheng, S, Wrensch, MR, Wiemels, JL, Nelson, HH, Karagas, MR, Padbury, JF, Bueno, R, Sugarbaker, DJ, Yeh, RF, Wiencke, JK, Kelsey, KT. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLOS Genetics 2009